1+ months

Organic Chemist: High Throughput Screening

Sandwich, IL 60548
Pfizer Purpose

Breakthroughs that change patients' lives... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives.

A laboratory focused position in the High Throughput Screening (HTS) Group of the Chemical Research & Development department (CRD). The position requires the application of High Throughput Screening methods, using state of the art technologies, to generate core data fundamental to synthetic route and manufacturing process design. That data provides the foundation for optimal design and development of safe, robust, scalable and efficient chemical processes for the manufacture of Active Pharmaceutical Ingredients (API's).


+ Practical organic chemistry:

+ The role is primarily laboratory based.

+ Design, execution and data interpretation of High Throughput Experiments specifically reaction, solubility and salt screens.

+ Design, execution and interpretation of multivariate experimentation approaches i.e.: DoE.

+ Efficient execution through the use of the latest technologies.

+ Maintain high safety standards at all times.

+ Proactive partnership with other scientists to design screens, interpret the resulting data and enable subsequent process development

+ Utilise the literature, computational tools and developing knowledge to design and interpret screening experiments.

+ Accountable for the scientific direction of work packages. May mentor and direct other colleagues providing technical guidance.

+ Maintain a high-quality lab notebook to good laboratory practise standards.

+ Convey work clearly and concisely to internal stakeholders through written and verbal communications.

+ Drive the utilization of the most contemporary and effective technologies and software.

Organisational Relationships

Partner with Chemistry, Engineering, Analytical and Manufacturing colleagues within Sandwich and additional Pfizer sites. Potential to work externally with other Pharmaceutical companies, external consultants and contractors.

Education and Experience

A PhD or Postdoc in organic chemistry, with an honours degree in chemistry, plus expertise in the application of high throughput screening methodologies.

Technical Skill Requirements

+ Extensive knowledge of Organic Chemistry e.g.: synthetic reagents, methodologies, reaction mechanisms, reaction work-ups and isolations consistent with qualification level.

+ Practise of conducting chemical reactions is essential, as is the application of High Throughput Screening methodologies such as automated small-scale reaction screening and screening in flow.

+ Possess a strong passion for the application and development of new technologies, software and computational chemistry.

+ Strong learning aptitude; desire and ability to learn organic chemistry, new techniques and embrace a continuous improvement philosophy to drive enhanced working approaches.

+ Self-motivated, hardworking and able to set personal goals which are both realistic and focused.

+ Enthusiastic attitude and approach to teamwork acting as role model with positive influencing and listening skills. Ability to work collaboratively and effectively within high performing teams as well as individually.

+ Rational and creative approach to problem solving. Ability to apply learning to new situations as well as trying new and untested approaches to solve problems.

+ Ability to evaluate information from a broad range of sources, draw sound conclusions and propose next steps.

+ Communicates verbally and in written form with clarity and purpose.


We aim to create a trusting, flexible workplace culture which encourages employees to achieve work life harmony, attracts talent and enables everyone to be their best working self. Let's start the conversation!

Equal Employment Opportunity

We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer iscommitted to celebratingthis,in all itsforms - allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees. **\#LI-PFE**

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

Research and Development


Posted: 2020-05-05 Expires: 2020-07-08

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Organic Chemist: High Throughput Screening

Sandwich, IL 60548

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