1+ months

Scientist (non

Pfizer
La Jolla, CA 92037
**ROLE SUMMARY**

The Cancer Immunology Discovery (CID) group in La Jolla, CA is focused on the generation of large molecule immunotherapeutics that promote anti-tumor activity or counter immunosuppression in the tumor microenvironment. CID's efforts are supported by a world class antibody generation program, and a commitment to effective biotherapeutic design that stresses both ingenuity and simplicity. Our team takes a holistic approach to understanding the interplay of tumor, stromal, and immune cells in the tumor microenvironment, striving to define the axes of intercellular communication that could be leveraged to generate novel therapeutics.

We are seeking a qualified candidate to join us at a Scientist level to contribute to our hybridoma generation and antibody characterization activities for the identification of novel biotherapeutics. The successful candidate will work closely with individuals in antibody production, protein engineering and immunology/oncology groups to innovate and develop the next-generation of protein therapeutics for cancer immunotherapy.

The successful candidate will demonstrate clear and professional verbal and written communication, maintain an electronic notebook, and present scientific results to collaborators and at team meetings. This position will not have any direct reports. There will be less than 5% travel.



**ROLE RESPONSIBILITIES**

Carry out hands-on lab work to assist in the generation of hybridomas and characterization of antibodies.

Cell-culture, ELISA, cloning, protein expression and purification (affinity chromatography, size exclusion chromatography using FPLC).

Experienced in Flow cytometry

Help to build a culture that embraces scientific excellence, continuous learning, and increasing the team's ability to deliver novel drug development opportunities through the rapid incorporation of emerging biotechnologies to ensure our team continues research on the leading-edge of oncology drug discovery.



**BASIC QUALIFICATIONS**

BS/MS in Biochemistry, Molecular Biology, or related discipline with a minimum of 2-5 years of laboratory experience. Previous industrial experience is strongly preferred.

Technical expertise should include antibody expression and purification, cell-culture.

**PREFERRED QUALIFICATIONS**

Antibody sequencing (RT-PCR), and antibody affinity measurements (SPR or BLI)

High-throughput screening of antibodies

Single cell sorting via FACS

Strong understanding of molecular biology and protein biochemistry.

Motivated, proactive, and eager to learn.

Excellent communication and presentation skills.

Advanced molecular design proficiency.

Hands-on experience with instruments such as GE AKTA Pure/Avant, Perkin-Elmer LabChip, liquid handling robots, Biacore T200 or 8K.



Other Information:

-Eligible for Employee Referral Bonus



\#LI-PFE



**Sunshine Act**

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**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

N (Other) (United States of America)

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

Categories

Posted: 2019-10-03 Expires: 2019-12-04

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Scientist (non

Pfizer
La Jolla, CA 92037

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