10 days old

Senior Associate Scientist, Biotherapeutic Protein Purification

Cambridge, MA 02139
**Senior Associate Scientist, Biotherapeutic Protein Purification**

Pfizer's BioMedicine Design (BMD) Biotherapeutic Expression and Purification group (BEP) is seeking a motivated protein purification scientist. Qualified candidate will play an essential role in a high-energy protein purification research laboratory. The purification group is responsible for non-GMP protein drug lead generation, supporting the various Pfizer research units and their pre-clinical therapeutic in-vitro and in-vivo needs. The candidate will be responsible for processing of mammalian- expressed recombinant protein modalities including, but not limited to, monoclonal antibodies through the use of state-of-the-art technologies and equipment. The candidate will contribute to the group wide deliverables and be required to work on several projects simultaneously presenting results and updates at group meetings.


+ Support the development of scalable protein purification processes, and e nsure timely delivery of highly purified biotherapeutic candidates to discovery project teams.

+ Assess quality of biotherapeutics rigorously and review all analytical documentation prior to protein release.

+ Routinely provide updates at project meetings.

+ Proactively evaluate new technologies and implement new features and functionality into discovery pipeline.

+ Will be involved in the design and execution of projects with the ability to operate independently.

+ Work closely with multidisciplinary teams including therapeutic discovery teams, research units, bioanalytical teams, transient expression and stable cell line development groups, engineering leads, and R&D project leaders.


+ BS with 2-4 years or MS with 0-3 years of relevant experience in Biochemistry, Biology, Biological Engineering or a related discipline along with a solid understanding of antibody/therapeutic protein purification.

+ Hands-on experience with protein purification (using affinity and traditional chromatographic techniques) on AKTA chromatography systems, including operating Unicorn and ChemStation software packages.

+ Hands-on experience with analytical biochemistry and experience in protein analytical characterization, including mass spectrometric analysis of protein.

+ Experience in protein expression and purification from HEK, CHO, E. coli systems.

+ Strong written and oral communication skills and ability to work effectively in cross functional teams.

+ Organized, detail oriented, multi-task, and remain flexible with changing needs.

+ Must be self-motivated and able to work under strict timeline.


+ Prior industry experience in antibodies/therapeutic protein purification.

+ Python and/or VB experience.

**Other Job Details:**

+ **Last Date to Apply for Job: February 26, 2021**

+ Eligible for Employee Referral Bonus: YES


**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development



Posted: 2021-02-19 Expires: 2021-03-21

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Senior Associate Scientist, Biotherapeutic Protein Purification

Cambridge, MA 02139

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