1+ months

Senior Associate Scientist, Gene Therapy Process Development

Pfizer
St Louis, MO 63103
**ROLE SUMMARY**

Gene therapy is a new and exciting therapeutic area. The purpose of the Associate Scientist position is to provide the planning and execution of experiments to design and optimize gene therapy manufacturing processes. The successful candidate will have a working knowledge of biochemistry, and related analytical chemistries, chromatography, centrifugation, precipitation, and filtration design principles. This position requires the design and execution of experiments using these technologies and the ability to evaluate and clearly reporting the results to laboratory colleagues and other affected functional areas.



**ROLE RESPONSIBILITIES**

The successful Senior Associate Scientist applicant will have experience in laboratory research and a desire to continue in a laboratory-focused role. This position will join a larger team of scientists across multiple sites focused on developing and optimizing recovery and purification processes for recombinant proteins and biological macromolecules for early- and late-phase clinical trials. The Senior Associate Scientist will be responsible for working with fellow scientists to develop robust, efficient, and scalable strategies for improving process performance. Responsibilities will include small-scale studies and pilot plant and manufacturing downstream purification studies. Based on the analyses of these studies, this position will be expected to develop and test new hypotheses to improve the fundamental understanding of recovery and purification processes. This position will support process validation, quality by design, regulatory approaches, and quality systems. This position will be expected to prepare internally reviewed technical reports, make oral presentations to scientists and management, and publish externally. The Senior Associate Scientist will be responsible for executing operational efficiency improvements and planning and implementing improvements across Bioprocess R&D work processes. The successful candidate must be able to endorse change to business infrastructure to ensure pipeline, legacy and technology success.



**BASIC QUALIFICATIONS**



+ Required: Bachelor's Degree with 2-4 years of experience or MS degree in a biological or engineering discipline (Biotechnology, Biochemistry, Chemical/Biochemical Engineering, or equivalent) with 0-2 years of experience

+ 0-2 years experience in recombinant protein/biomolecule purification process development, technology transfer and/or bioprocess manufacturing required.

+ Experience with protein chemistry, protein analytics, and bioprocess technology, including the recent scientific literature, is required.

+ Analytical and computer skills are required.



**PREFERRED QUALIFICATIONS**



+ Demonstrated ability to drive for results and generate innovative research programs independently

+ Applicants should be bright, organized, self-motivated, and capable of working independently, and in a collaborative environment.

+ The successful candidate will possess strong oral and written communication skills.

+ Diverse work experience recovering recombinant proteins/biomolecules from mammalian and microbial/yeast cultures.

+ Experience transferring Biotherapeutic processes to pilot plants or manufacturing organizations, and knowledge of data acquisition and controls systems in these environments is desirable.

+ Sound understanding of statistical experimental design and analysis is a benefit.

+ It would be advantageous for the successful candidate to have a strong working knowledge of the drug development process for progression of a biological candidate.



**ADDITIONAL OFFER DETAILS**



+ Additional Location Information: St. Louis, MO

+ Eligible for Employee Referral Bonus: Yes



**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.



**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.



**\#LI-PFE**



Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

Categories

Posted: 2019-10-31 Expires: 2020-01-01

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Senior Associate Scientist, Gene Therapy Process Development

Pfizer
St Louis, MO 63103

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