1+ months

Senior Manager, Toxicology Nonclinical Development

West Chester, PA 19380
Company Info
Teva is a global pharmaceutical leader and the world's largest generic medicines producer, committed to improving health and increasing access to quality health solutions worldwide. Our employees are at the core of our success, with colleagues in over 80 countries delivering the world's largest medicine cabinet to 200 million people every day. We offer a uniquely diverse portfolio of products and solutions for patients and we've built a promising pipeline centered around our core therapeutic areas. We are continually developing patient-centric solutions and significantly growing both our generic and specialty medicines business through investment in research and development, marketing, business development and innovation. This is how we improve health and enable people to live better, healthier lives. Join us on our journey of growth!
Job Description

The nonclinical toxicologist will have a background in Biology or in a relevant field along with drug development experience in the pharmaceutical industry.

You will be part of a skilled global department leading the scientific understanding of the safety of novel therapeutics (primarily biologics) in a company dedicated to finding therapies for various disease disorders. You will be expected to execute and monitor nonclinical safety studies and interpret findings from these studies in support of clinical development.

In addition, you must have an applied background in chemistry with knowledge in writing risk assessment documents in various nonclinical safety fields, including non-API impurities (eg. extractables/leachables), and knowledge of applicable regulations to support Tevas pipeline.

Furthermore, there may be need to provide safety assessment support to the development of generic products. Your communication skills at all levels of interaction must be excellent, as you will work closely with colleagues within the organization.

Additional Responsibilities:

  • Develop a nonclinical safety plan to support clinical development and meet regulatory requirements.
  • Design, monitor and coordinate the conduct of GLP and non-GLP toxicology studies at CROs in line with project timelines and budget.
  • Understand the basic biology of the intended target of drug candidates and mechanisms of toxicity observed non-clinically and/or clinically in order to drive mitigation and/or back-up strategies to minimize potential harm to patients.
  • Write nonclinical safety documents relating to the project, including nonclinical sections of regulatory submission documents, and participate in regulatory meetings.
  • Write risk assessment documents for impurities (eg, extractables and leachables, degradation products, etc.).
  • Present data and interpretations in written and oral form to management and internal forums.
  • Build collaborative networks to facilitate cross-functional communication and activities.
Qualifications

Required Qualifications:

  • Master's degree in toxicology, biology or a related life-science field (eg Pharmacology/Pharmaceutics/Biochemistry, DVM, PharmD)
  • Minimum 4 years of toxicology experience in pharmaceutical/biotech/CRO setting performing drug development activities such as: designing and monitoring nonclinical studies, interpreting data, generating reports and regulatory documents

Preferred Qualifications:

  • PhD in Toxicology or related life science field of study
  • Experience in nonclinical safety assessment throughout all stages of drug development, especially with biologics
  • Experience in scientific investigation of fundamental toxicology issues, either through scientific publications or drug development experience
  • An accredited or registered toxicologist
Function
Research & Development
Sub Function
Drug Development and Preclinical Studies
Reports To

Director, Nonclinical Safety Assessment

Already Working @TEVA?

If you are a current Teva employee, please apply using the internal career site available on "Employee Central". By doing so, your application will be treated with priority. You will also be able to see opportunities that are open exclusively to Teva employees. Use the following link to search and apply: Internal Career Site

The internal career site is available from your home network as well. If you have trouble accessing your EC account, please contact your local HR/IT partner.

Categories

Posted: 2020-10-30 Expires: 2020-12-31

Join us at the forefront of pharmaceutical research and production. With state-of-the-art facilities, highly skilled colleagues, and a high-powered organizational culture, Teva offers you countless possibilities to make a real difference in people's lives and add value to your career.

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Senior Manager, Toxicology Nonclinical Development

Teva Pharmaceuticals
West Chester, PA 19380

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