1+ months

Senior Scientist

La Jolla, CA 92037

The Cancer Immunology Discovery (CID) group in La Jolla, CA is dedicated to developing therapeutics that redirect the immune system against cancer. CID researchers apply the latest scientific knowledge and approaches to discover truly innovative Immuno-Oncology therapeutics.

We are seeking a qualified candidate to join us at a Senior Scientist level within the Leukocyte Signaling CID group. Responsibilities include leveraging cell biologic tools to dissect mechanisms-of-action of new therapeutics, identify new targets and drug combinations, and develop biomarkers and drug screening assays. Expertise in cell biology, signaling, and biochemistry is vital for this position. Highly-qualified candidates will have a developed interest in transcriptomics/RNAseq, phospho-proteomics, and cellular immunology.

The successful candidate will work closely with individuals in drug design and immune-oncology groups to innovate and develop the next-generation immunotherapies.


+ Carry out hands-on lab work to apply cell biology, molecular biology, and biochemistry techniques to investigate the effects of therapeutics on the immune system.

+ Prepare samples for transcriptomic, proteomic, and epigenetic studies, and lead efforts to analyze and confirm findings.

+ Design, assess, and troubleshoot cell-based assays with primary immune cells and immortalized cell lines.

+ Collaborate with protein engineers, chemists, and immunologists to identify novel therapeutics.

+ Participate and present in internal and external collaboration meetings as well as at site and cross-site meetings.

+ Communicate experimental findings accurately and concisely in both oral and written formats.

+ Help to build a culture that embraces scientific excellence and continuous learning.


+ PhD in Biology/Immunology/Biochemistry/Cell Biology, or related discipline

+ Expertise in primary and immortalized cell culture, cell-based assays, FACS, western blotting, and interrogating signaling pathways.

+ Ability to independently design, plan, and execute and interpret experiments

+ Experience with data analysis and presentation software

+ Familiarity with antibody and small-molecule discovery approaches.

+ Excellent written and oral communication skills

+ The individual should be scientifically creative and driven by a willingness to embrace innovation within drug discovery, and an eagerness to challenge and meet timelines

+ The ability to work closely with other group members within teams is essential


+ Postdoctoral or industry R&D experience

+ Strong track record of scientific accomplishments demonstrated through publications in highly-impact journals and/or intellectual property generation.

+ Track record of demonstrating analytical skills and unique problem-solving skills

+ Prior experience in working with omics approaches including RNAseq, ATAC-seq and/or phospho-proteomics.

Other Information:

-Eligible for Employee Referral Bonus

-Eligible for Relocation Benefit


**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.


Posted: 2019-10-04 Expires: 2019-12-04

Before you go...

Our free job seeker tools include alerts for new jobs, saving your favorites, optimized job matching, and more! Just enter your email below.

Share this job:

Senior Scientist

La Jolla, CA 92037

Join us to start saving your Favorite Jobs!

Sign In Create Account
Powered ByCareerCast